As an Obama supporter and a person who is truly baffled that anyone can muster genuine enthusiasm for Clinton on her own terms (though if she's the nominee I'll be plenty enthused to see her beat whatever paleolithic hairball the Republicans cough up), I wish Matthews would shut the hell up already.
Good gravy, the man's a train wreck! The only rational explanation for his continued mouth-diarrhea about Clinton is that he actually wants her to win the primary and is doing his best to make her opponents seem like misogynist knuckle-draggers. A move like Romney's anti-Mormon push polling.
The only problem with that analysis is that such jiu-jitsu requires a metric ton more intelligence than Matthews ordinarily manifests. So I'm left to the conclusion that there simply is no rational explanation for his continued dipshittery, just some deep-seated loathing for Hillary Clinton that probably comes from his own unrecognized humiliation at having been a part of the two year journalistic search party down Bill Clinton's pants that put us directly in the hell we've enjoyed for the last seven.
My advice below still stands, though-he should simply be ignored. Changing your vote because a pundit pisses you off is totally irrational.